Eastern and Southern Africa are regions highly susceptible to the adverse effects of climate change; which exacerbate existing social inequalities and disproportionately impact marginalized populations; particularly women; girls; and children. The intersection of the care economy; childcare; gender equality; and climate change is critical in understanding and addressing these vulnerabilities. Climate-induced disasters and environmental changes disrupt childcare[1] practices; increase health risks; and strain educational systems; negatively affecting children’s overall well-being. These disruptions intensify the caregiving responsibilities traditionally shouldered by women; limiting their participation in economic activities and adaptive strategies; and reinforcing existing gender inequalities.Current climate adaptation policies often overlook the gender-climate-childcare nexus; resulting in inadequate support for women’s empowerment and children’s resilience. Innovative; gender-transformative approaches are needed to address this triple nexus and inform more effective climate resilience policies and practices. This assessment seeks to explore the complex interplay between care economy dynamics; childcare responsibilities; and climate change impacts in Eastern and Southern Africa; focusing on how these factors create compounded vulnerabilities for women; girls; and children; especially those from marginalized groups.[1] ¹ Childcare refers to services primarily aimed at caring for children while parents are working or otherwise unavailable. Quality childcare ensures children are safe and have opportunities to learn and form positive relationships. It usually caters to children from birth to primary-school-entry age (typically 5-6 years) but can also include after-school care. Childcare can be center-based (e.g.; daycares; nurseries); home-based; or provided through family and informal arrangements. Preschool can serve a dual role in preparing children for school and supporting working parents by offering full-day services.